This book is a series of reports jointly contributed by the Chinese Academy of Sciences and other relevant nation-level institutions in China. It summarizes and analyses the overall construction situation and development trend of China's e-Science, focusing on strategic developments, application practices and infrastructure construction, and comprehensively demonstrates the new situation, progress and achievements of China's e-Science in the past two years. The book is rich in content, detailed cases, and has good reference value for the future development of research informatization.