The threats of emerging diseases have shaken certainties about health systems, the effectiveness of governance, lifestyles and the reality of national sovereignty. The Covid-19 Crisis analyzes the global issues related to the emergence of the SARS-CoV-2 virus through investigations and reflections related to both the epidemic itself (epidemiology, computerized surveillance tools and vaccines) and to the societal issues it raises (work, innovation, religious practices, behaviors and societal models). This eclectic approach highlights scientific working methods that meet the requirements of health crises, as well as technical solutions and societal practices adapted to epidemic situations. It also presents feedback and testimonies.