Our oral cavity is always considered as the mirror of our general health. It is said that almost all the early stages of various systemic diseases are manifested in the oral cavity. a thorough understanding of the oral manifestations of these systemic conditions helps us in diagnosing them at the very grass root level and thereby treat them without much complications. these signs are often neglected by the dental practitioners mostly due to lack of adequate knowledge regarding the same. Hence this book throws an insight into various oral manifestations of systemic diseases.